Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 854
interventional 729
Observational 122
Registry 3

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 367
Biological 123
Drug|placebo 47
Other 34
Biological|Other 23
Biological|Drug 21
Behavioral 17
Device 15
Biological|placebo 13
Dietary Supplement 11
Drug|Other 9
Biological|Drug|placebo 7
Procedure 5
Dietary Supplement|Drug 4
Dietary Supplement|placebo 4
Biological|Drug|Other 3
Biological|Procedure 3
Device|Drug 3
Other|Procedure 3
Combination Product 2
Device|Other 2
Diagnostic Test 2
Behavioral|Drug 1
Behavioral|Drug|Other 1
Behavioral|Procedure 1
Biological|Device 1
Biological|Dietary Supplement 1
Biological|Other|placebo 1
Diagnostic Test|Drug 1
Diagnostic Test|Procedure 1
Drug|Other|placebo 1
Drug|Procedure 1
Other|placebo 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 76
United Kingdom 45
Kenya 42
Tanzania 39
Uganda 35
NA 34
Burkina Faso 33
Mali 29
Ghana 24
Netherlands 24
Gambia 21
Thailand 19
Malawi 17
Gabon 13
Indonesia 13
Mozambique 13
Cambodia 11
Australia 10
Senegal 9
Brazil 8
Colombia 8
Zambia 8
Guinea-Bissau 7
Nigeria 7
Switzerland 7
Congo, The Democratic Republic of the 6
Vietnam 6
Afghanistan 5
Benin 5
China 5
Ethiopia 5
Bangladesh 4
Germany 4
Pakistan 4
Rwanda 4
South Africa 4
Sudan 4
Belgium 3
Burkina Faso|Mali 3
Equatorial Guinea 3
France 3
Malaysia 3
Papua New Guinea 3
Sierra Leone 3
United States|Kenya 3
Burkina Faso|France 2
Côte D’Ivoire 2
Cameroon 2
Congo 2
India 2
Kenya|Tanzania 2
Namibia 2
Peru 2
Thailand|Vietnam 2
United States|Mali 2
Afghanistan|Ethiopia|Indonesia|Vietnam 1
Bangladesh|Brazil|Cambodia|Ethiopia|India|Peru|Philippines|Thailand 1
Bangladesh|Cambodia|Congo, The Democratic Republic of the|India|Lao People’s Democratic Republic|Myanmar|Thailand|Vietnam 1
Bangladesh|Ethiopia|Indonesia 1
Benin|Burkina Faso|Congo, The Democratic Republic of the|Gabon|Mozambique|Uganda|Vietnam 1
Benin|Burkina Faso|Congo|Nigeria|Togo 1
Benin|Burkina Faso|Gabon|Kenya|Uganda 1
Benin|Burkina Faso|Gambia 1
Benin|Gabon|Kenya|Mozambique|Tanzania 1
Benin|Kenya|Mali|Mozambique|Tanzania 1
Brazil|Colombia|Ethiopia|Peru|Thailand|Vietnam 1
Brazil|French Guiana|Suriname 1
Burkina Faso|Côte D’Ivoire|Ghana|Kenya|Mali 1
Burkina Faso|Cambodia|Côte D’Ivoire|India|Tanzania|Thailand|Vietnam 1
Burkina Faso|Congo, The Democratic Republic of the|Côte D’Ivoire|Gabon|Kenya|Mali|Mozambique|Philippines 1
Burkina Faso|Congo, The Democratic Republic of the|Gambia|Mozambique|Tanzania 1
Burkina Faso|Gabon|Gambia|Kenya|Mali|Mozambique|Thailand|Uganda|Vietnam 1
Burkina Faso|Gabon|Ghana|Kenya|Malawi|Mozambique|Tanzania 1
Burkina Faso|Gabon|Mozambique|Nigeria|Rwanda|Uganda|Zambia 1
Burkina Faso|Gambia|Ghana|Mali 1
Burkina Faso|Ghana 1
Burkina Faso|Ghana|Kenya|Malawi|Senegal|Tanzania 1
Burkina Faso|Ghana|Kenya|Mali|Senegal|Zambia 1
Burkina Faso|Ghana|Kenya|Nigeria|Tanzania 1
Burkina Faso|Ghana|Malawi|Zambia 1
Burkina Faso|Ghana|Mali|Nigeria 1
Burkina Faso|Ghana|Rwanda 1
Burkina Faso|Ghana|Uganda 1
Burkina Faso|Kenya|Tanzania 1
Burkina Faso|Senegal 1
Cambodia|Gambia|Indonesia|Senegal|Thailand|Uganda 1
Cambodia|India|Indonesia|Thailand 1
Cambodia|Lao People’s Democratic Republic|Myanmar|Thailand|Vietnam 1
Cambodia|Vietnam 1
Cameroon|Congo, The Democratic Republic of the|Congo|Côte D’Ivoire|Gabon 1
Cameroon|Madagascar|Mali|Senegal 1
Cameroon|Mali|Rwanda|Sudan 1
Cameroon|Nigeria 1
Cameroon|Senegal 1
Canada|Ethiopia 1
Colombia|India 1
Colombia|Vietnam 1
Congo, The Democratic Republic of the|Gambia|Ghana|Indonesia|Kenya|Mali|Mozambique|Philippines|Senegal 1
Congo, The Democratic Republic of the|Madagascar|Mozambique|Nigeria 1
Congo|Uganda 1
Gabon|Ghana|Mali|Rwanda|Uganda 1
Gabon|Ghana|Tanzania 1
Gabon|Kenya 1
Gabon|Malawi 1
Gabon|Mozambique 1
Gambia|Malawi 1
Gambia|Zambia 1
Ghana|Kenya 1
Ghana|Mali|Uganda|Zambia| 1
India|Tanzania|Thailand 1
Ireland 1
Japan 1
Kenya|Malawi|Tanzania 1
Kenya|Nigeria|Tanzania 1
Kenya|Thailand 1
Kenya|Uganda 1
Korea, Republic of 1
Lao People’s Democratic Republic 1
Liberia 1
Malawi|Uganda|Zambia 1
Malawi|Zambia 1
Mozambique|South Africa|Swaziland 1
Myanmar 1
Niger 1
Philippines 1
Spain 1
Swaziland 1
Switzerland|Tanzania 1
Taiwan 1
United States|Burkina Faso 1
United States|Mozambique 1
Vietnam|Bangladesh|Cambodia|Congo, The Democratic Republic of the|India|Kenya|Lao People’s Democratic Republic|Myanmar|Nigeria|Thailand 1

Sites per Study

Site_count Study_Count
1 558
2 76
3 36
4 16
5 10
6 4
7 8
8 6
9 5
10 5
13 1
14 2
19 1
20 1

Phase

Phase Study_Count
Phase 1 162
N/A 157
Phase 4 119
Phase 3 116
Phase 2 89
Phase 1/Phase 2 58
Phase 2/Phase 3 23
Early Phase 1 5

Number of Arms

Number_of_Arms Count_of_Studies
1 71
2 248
3 122
4 75
5 21
6 21
7 13
8 7
9 3
10 3
11 3
12 2
13 5
15 2
17 1
23 1
30 1
NA 130

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 18.0 2.000 0.0000 7.0000 11.0000 20.0 10.000 16.000
1st Qu. 18.0 122.250 26.0000 24.0000 60.0000 193.0 305.000 211.500
Median 23.0 700.000 40.5000 42.0000 120.0000 361.0 644.000 430.000
Mean 37.8 8062.875 99.7284 104.3448 269.2529 886.0 2336.722 5310.379
3rd Qu. 25.0 2800.000 67.7500 80.2500 292.0000 1247.5 1355.000 1627.500
Max. 105.0 240502.000 4556.0000 900.0000 2116.0000 3642.0 90000.000 393387.000

Trial Group Type

group_type Group_Count
Experimental 1127
Active Comparator 440
Placebo Comparator 164
NA 130
No Intervention 93
Other 63
Sham Comparator 3

Intervention Model

intervention_model Study_Count
Parallel Assignment 546
Single Group Assignment 130
Factorial Assignment 21
Crossover Assignment 14
NA 10
Sequential Assignment 8

Primary Purpose

primary_purpose Study_Count
Treatment 322
Prevention 280
Basic Science 32
Diagnostic 23
Other 23
Health Services Research 21
NA 18
Screening 4
Educational/Counseling/Training 3
Supportive Care 3

Observational Studies

Studies by Country

Country Study_Count
Mali 20
Uganda 10
United States 9
Thailand 7
Burkina Faso 6
France 5
NA 5
Cambodia 4
Kenya 4
Myanmar 4
Tanzania 4
Bangladesh 3
Brazil 3
Congo, The Democratic Republic of the 3
Ghana 3
Gambia 2
Ghana|Kenya|Malawi 2
Indonesia 2
Malawi 2
Peru 2
Afghanistan 1
Benin 1
Bhutan 1
Burkina Faso|Gabon|Ghana|Kenya|Malawi|Tanzania 1
Burkina Faso|Ghana|Kenya 1
Cambodia|Lao People’s Democratic Republic|Thailand|Vietnam 1
Chad 1
Congo, The Democratic Republic of the|Madagascar|Mozambique|Nigeria 1
Congo, The Democratic Republic of the|Nigeria|Uganda 1
Gabon|Ghana 1
Germany|Ghana 1
Ghana|Kenya 1
Guinea 1
India 1
Malaysia 1
Nigeria 1
Rwanda 1
Senegal 1
South Africa 1
Tanzania|Uganda 1
Zambia 1
Zimbabwe 1

Sites per Study

Site_count Study_Count
1 99
2 10
3 4
4 3
5 2
6 1
7 1
8 1
9 1

Enrollment Metrics

Measure Observational
Min 1.000
1st Qu 278.000
Median 600.000
Mean 4646.579
3rd Qu 2008.000
Max 150000.000

Observation Model

observational_model Study_Count
Cohort 55
NA 32
Case-Only 11
Other 8
Case-Control 7
Case Control 3
Ecologic or Community 3
Case-Crossover 1
Defined Population, Natural History 1
Family-Based 1

Time Perspective

time_perspective Study_Count
Prospective 89
Cross-Sectional 19
NA 7
Other 3
Retrospective 3
Longitudinal, Prospective 1

Registries

Studies by Country

Country Study_Count
NA 2
Bangladesh 1

Sites per Study

Site_count Study_Count
1 3

Enrollment Metrics

Measure Registries
Min 156
1st Qu 250
Median 344
Mean 554
3rd Qu 753
Max 1162

Registry Model

observational_model Study_Count
Case-Control 1
Case-Only 1
Ecologic or Community 1

Time Perspective

time_perspective Study_Count
Prospective 2
Cross-Sectional 1

Follow-up

target_duration Study_Count
14 Days 1
28 Days 1
6 Months 1

Overview of Studies

Interventional Trials

#If less then 500 trials

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT00471302 Normal Immunological Parameters Among Healthy Volunteers in Kambila, Mali https://ClinicalTrials.gov/show/NCT00471302 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT04105855 Malaria Prevalence Around Maferinyah, Guinea https://ClinicalTrials.gov/show/NCT04105855 Recruiting National Institutes of Health Clinical Center (CC) 2022-04-30
NCT03307369 A Retrospective Study of Severe Plasmodium Vivax https://ClinicalTrials.gov/show/NCT03307369 Active, not recruiting University of Oxford 2019-06-30
NCT03281291 An Ancillary Study Protocol to GSK’s Phase IIb Malaria Vaccine Trial Entitled “Efficacy, Safety and Immunogenicity Study of GSK Biologicals’ Candidate Malaria Vaccine (SB257049) Evaluating Schedules With or Without Fractional Doses, Early Dose 4 and Yearly Doses, in Children 5-17 Months of Age” https://ClinicalTrials.gov/show/NCT03281291 Active, not recruiting GlaxoSmithKline 2021-06-21
NCT03224052 Empirical ANtibiotic THErapy in Adults Hospitalised With Malaria https://ClinicalTrials.gov/show/NCT03224052 Completed Menzies School of Health Research 2017-10-31
NCT03217851 Prevalence Survey of Antimalarial Drug Resistance Markers https://ClinicalTrials.gov/show/NCT03217851 Recruiting University of Oxford 2020-08-31
NCT03132402 ELISA Validation of Hypersensitive Rapid Diagnostic Test Results for Detection of P. Falciparum https://ClinicalTrials.gov/show/NCT03132402 Completed University of Oxford 2018-01-01
NCT02974608 Impact of Malaria on Pregnant Women in Ouelessebougou, Mali https://ClinicalTrials.gov/show/NCT02974608 Recruiting National Institutes of Health Clinical Center (CC) 2021-01-31
NCT02932072 Field Evaluation of a Device for Automated Malaria Microscopy (Autoscope Version 2) https://ClinicalTrials.gov/show/NCT02932072 Active, not recruiting University of Oxford 2019-12-31
NCT02903706 Prevalence of Malaria Parasites in People Working in Illegal Gold Mining in French Guiana https://ClinicalTrials.gov/show/NCT02903706 Completed Centre Hospitalier de Cayenne 2015-06-30
NCT02895568 Prevalence Survey of Plasmodium Falciparum Antimalarial Drug Resistance Markers https://ClinicalTrials.gov/show/NCT02895568 Completed University of Oxford 2018-09-06
NCT02817919 Cohort Event Monitoring in Sub Saharan Africa https://ClinicalTrials.gov/show/NCT02817919 Completed African Collaborating Centre for Pharmacovigilance 2017-03-31
NCT02800109 Child Follow-up Until 2 Years https://ClinicalTrials.gov/show/NCT02800109 Completed University of Oxford 2018-02-28
NCT02793336 Early Life Cohort in Papua Indonesia (ELIPI Study) https://ClinicalTrials.gov/show/NCT02793336 Recruiting Menzies School of Health Research 2020-07-31
NCT02792816 Molecular Surveillance of Artemisinin Resistance Malaria in Myanmar https://ClinicalTrials.gov/show/NCT02792816 Completed Department of Medical Research, Lower Myanmar 2013-12-31
NCT02769013 Assessing the Effect of Neglected Tropical Diseases on Plasmodium Falciparum Transmission in an Area of Co-endemicity https://ClinicalTrials.gov/show/NCT02769013 Recruiting University Hospital Tuebingen 2019-10-31
NCT02708199 Molecular Assessment of Drug Resistance Markers in Asymptomatic Malaria Cases and Malaria Antibody Kinetic https://ClinicalTrials.gov/show/NCT02708199 Completed Department of Medical Research, Lower Myanmar 2015-12-31
NCT02700269 Vanderbilt-Zambia Innovations in Global Health Technologies https://ClinicalTrials.gov/show/NCT02700269 Completed Macha Research Trust, Zambia 2019-02-28
NCT02669823 Optimizing Sysmex Technology as an Innovative Tool to Differentiate Between Malaria (PALUdism) and BACterial Infections in a Malaria Endemic Region https://ClinicalTrials.gov/show/NCT02669823 Completed Sysmex Europe GmbH 2017-06-30
NCT02659566 Impact of Antimalarial Treatment on Measures of T Cell Suppression/Regulation in Healthy Adults From Doneguebougou, Mali https://ClinicalTrials.gov/show/NCT02659566 Completed National Institutes of Health Clinical Center (CC) 2018-06-12
NCT02639299 Screening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human Malaria Challenge https://ClinicalTrials.gov/show/NCT02639299 Recruiting National Institutes of Health Clinical Center (CC) 2025-09-30
NCT01265407 Malaria Surveillance in Rakai, Uganda https://ClinicalTrials.gov/show/NCT01265407 Completed National Institutes of Health Clinical Center (CC) NA
NCT02557425 Prophylaxis Against Malaria to Enhance Child Development (PROTECT Study) https://ClinicalTrials.gov/show/NCT02557425 Active, not recruiting Indiana University 2021-12-31
NCT02544048 Markers of T Cell Suppression: Antimalarial Treatment and Vaccine Responses in Healthy Malian Adults https://ClinicalTrials.gov/show/NCT02544048 Completed National Institutes of Health Clinical Center (CC) 2015-09-04
NCT02471378 Laboratory Evaluation of Pregnancy Malaria Vaccine Candidates/In-vitro Testing of Pregnancy Malaria Vaccine Candidates https://ClinicalTrials.gov/show/NCT02471378 Recruiting National Institutes of Health Clinical Center (CC) 2021-06-30
NCT02451904 Severe and Cerebral Malaria Investigated Through Host Metabolomics https://ClinicalTrials.gov/show/NCT02451904 Completed University of Oxford 2017-09-30
NCT02427360 Evaluating the Efficacy of Artesunate-mefloquine and the Relative Roles of Resistance Genetic Markers https://ClinicalTrials.gov/show/NCT02427360 Completed University of Oxford 2015-12-31
NCT02374450 A Surveillance Study of Diseases Specified as Adverse Events of Special Interest, of Other Adverse Events Leading to Hospitalisation or Death, and of Meningitis in Children in Africa Prior to Implementation of the RTS,S/AS01E Candidate Vaccine https://ClinicalTrials.gov/show/NCT02374450 Active, not recruiting GlaxoSmithKline 2022-07-20
NCT02371395 Validation of RealAmp Method for the Diagnosis of Malaria in Endemic Areas of Brazil https://ClinicalTrials.gov/show/NCT02371395 Completed Centers for Disease Control and Prevention 2015-06-30
NCT02353494 Efficacy and Safety of Dihydroartemisinin-piperaquine (DHP) for the Treatment of Uncomplicated Malaria https://ClinicalTrials.gov/show/NCT02353494 Completed Menzies School of Health Research 2016-05-31
NCT02206451 Assessing Human-to-Mosquito Transmission in Volunteers Participating in Malaria Vaccine Candidate Trials in Mali https://ClinicalTrials.gov/show/NCT02206451 Completed National Institutes of Health Clinical Center (CC) 2014-07-16
NCT03384498 Malaria Genetic Surveillance https://ClinicalTrials.gov/show/NCT03384498 Recruiting University of Oxford 2019-10-31
NCT03384472 Malaria Genetic Surveillance in Cambodia https://ClinicalTrials.gov/show/NCT03384472 Completed University of Oxford 2017-02-01
NCT02094508 Impact of TMP-SMX Prophylaxis on Malaria Infection and Immunity in Children in Uganda https://ClinicalTrials.gov/show/NCT02094508 Completed National Institutes of Health Clinical Center (CC) 2015-12-28
NCT01283165 Worm Infestation and Child Health in Zimbabwe https://ClinicalTrials.gov/show/NCT01283165 Completed University of Zimbabwe 2006-06-30
NCT02645604 Artemether-lumefantrine Resistance Monitoring in Children With Uncomplicated Plasmodium Falciparum Malaria in Mali https://ClinicalTrials.gov/show/NCT02645604 Completed National Institutes of Health Clinical Center (CC) 2018-12-14
NCT01921413 Clinical Performance Evaluation of Fyodor Urine Malaria Test (UMT) https://ClinicalTrials.gov/show/NCT01921413 Completed Fyodor Biotechnologies Inc 2014-02-28
NCT01843764 Rapid Diagnostic Tests for Assessment of Initial Clearance and Detection of Recurrent Malaria Infections https://ClinicalTrials.gov/show/NCT01843764 Completed Karolinska University Hospital 2011-04-30
NCT01828333 Malaria Treatment With Injectable ArteSunate https://ClinicalTrials.gov/show/NCT01828333 Completed Swiss Tropical & Public Health Institute 2013-06-30
NCT01736319 Artemisinin-resistant Malaria in Cambodia https://ClinicalTrials.gov/show/NCT01736319 Completed National Institutes of Health Clinical Center (CC) NA
NCT01716260 Safety and Efficacy of Chloroquine and Primaquine for Vivax Malaria in Bhutan https://ClinicalTrials.gov/show/NCT01716260 Completed Menzies School of Health Research 2015-10-31
NCT01545115 Study of the Environmental Factors Modulating Children Immune Response in Northern Senegal https://ClinicalTrials.gov/show/NCT01545115 Completed Biomedical Research Center EPLS 2010-02-28
NCT03806465 Malaria Vaccine Evaluation Programme https://ClinicalTrials.gov/show/NCT03806465 Active, not recruiting World Health Organization 2022-12-31
NCT01325974 Time to Become Negative of Three Rapid Diagnostic Tests for Malaria https://ClinicalTrials.gov/show/NCT01325974 Completed Epicentre 2013-02-28
NCT01322581 A Longitudinal Systems Biological Analysis of Naturally Acquired Malaria Immunity in Mali https://ClinicalTrials.gov/show/NCT01322581 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT03304704 Community Dynamics of Malaria Transmission and Mosquito Feeding in Bancoumana, Mali https://ClinicalTrials.gov/show/NCT03304704 Recruiting National Institutes of Health Clinical Center (CC) 2020-12-31
NCT04412005 Pregnant Women for Malaria Surveillance https://ClinicalTrials.gov/show/NCT04412005 Completed Barcelona Institute for Global Health 2019-10-31
NCT04327440 RTSS Vaccine and PBO Net Impact on Malaria Infection and Transmission in Malawi https://ClinicalTrials.gov/show/NCT04327440 Recruiting Michigan State University 2023-03-31
NCT04265573 Feasibility, Acceptability and Costs of a Multiple First-lines Artemisinin-based Combination Therapies https://ClinicalTrials.gov/show/NCT04265573 Recruiting Groupe de Recherche Action en Sante 2020-12-01
NCT04230161 Estimating the Malaria Prevention Impact of New Nets: Observational Analyses to Evaluate the Evidence Generated During Piloted New Net Distributions in Rwanda https://ClinicalTrials.gov/show/NCT04230161 Recruiting PATH 2022-09-01
NCT04176029 Lung Ultrasound in Children With Severe Malaria https://ClinicalTrials.gov/show/NCT04176029 Recruiting University of Oxford 2020-08-01
NCT04157894 Estimating the Malaria Prevention Impact of New Nets: Observational Analyses to Evaluate the Evidence Generated During Piloted New Net Distributions in Burkina Faso https://ClinicalTrials.gov/show/NCT04157894 Recruiting PATH 2022-09-01
NCT04050566 Malaria Birth Cohort https://ClinicalTrials.gov/show/NCT04050566 Recruiting Bernhard Nocht Institute for Tropical Medicine 2021-04-30
NCT03998839 TIPTOP Sulfadoxine-pyrimethamine (SP) Drug Resistance Study https://ClinicalTrials.gov/show/NCT03998839 Enrolling by invitation Jhpiego 2022-02-28
NCT03988296 Molecular Diagnostic Methods for Detection of Plasmodium Knowlesi https://ClinicalTrials.gov/show/NCT03988296 Completed Duke University 2019-08-22
NCT03955263 Malaria In Pregnancy in Central India https://ClinicalTrials.gov/show/NCT03955263 Active, not recruiting Lata Medical Research Foundation, Nagpur 2019-01-31
NCT03937817 Collection of Human Biospecimens for Basic and Clinical Research Into Alpha Globin Variants https://ClinicalTrials.gov/show/NCT03937817 Recruiting National Institutes of Health Clinical Center (CC) 2028-07-31
NCT01829737 Malaria Transmission Studies in Mali https://ClinicalTrials.gov/show/NCT01829737 Completed National Institutes of Health Clinical Center (CC) 2015-01-20
NCT03855995 A Study to Evaluate the Safety, Effectiveness and Impact of the GlaxoSmithKline Biologicals’ Malaria Vaccine- RTS, S/AS01E in Young Children in Sub-Saharan Africa https://ClinicalTrials.gov/show/NCT03855995 Recruiting GlaxoSmithKline 2025-03-12
NCT01717885 Antimalarial Pharmacology in Children and Pregnant Women in Uganda https://ClinicalTrials.gov/show/NCT01717885 Completed University of California, San Francisco 2015-12-31
NCT03648411 Drug Resistance Among Asymptomatic Infection https://ClinicalTrials.gov/show/NCT03648411 Recruiting Department of Medical Research, Lower Myanmar 2019-12-30
NCT03641534 Monitoring of Perfusion in Sepsis and Malaria https://ClinicalTrials.gov/show/NCT03641534 Recruiting University of Oxford 2019-09-30
NCT03594084 Malaria in Strasbourg University Hospital https://ClinicalTrials.gov/show/NCT03594084 Recruiting University Hospital, Strasbourg, France 2019-08-31
NCT03568344 Community Access to Rectal Artesunate for Malaria https://ClinicalTrials.gov/show/NCT03568344 Active, not recruiting Swiss Tropical & Public Health Institute 2020-05-31
NCT03512678 Evaluation of a Digital Microscope for Malaria https://ClinicalTrials.gov/show/NCT03512678 Recruiting University of Oxford 2019-12-31
NCT01255605 Impact of IPT With Sulfadoxin Pyrimetamin on Pregnant Women and Their Babies Outcomes in Peri-urban Areas of Bobo-Dioulasso(Burkina Faso) https://ClinicalTrials.gov/show/NCT01255605 Completed Université Polytechnique de Bobo-Dioulasso NA
NCT01240603 Plasmodium Falciparum Clearance Rates in Response to Artesunate in Eastern Cambodia https://ClinicalTrials.gov/show/NCT01240603 Completed National Institutes of Health Clinical Center (CC) NA
NCT01232530 Pharmacovigilance for ACTs in Africa https://ClinicalTrials.gov/show/NCT01232530 Completed Centre Muraz 2012-12-31
NCT01228344 Surveillance of Effectiveness/Safety of Artemether-lumefantrine in Patients With Malaria https://ClinicalTrials.gov/show/NCT01228344 Completed Novartis 2015-09-30
NCT01214876 Correlating Protection Against Malaria With Serum Profiles Against Plasmodium Falciparum Antigen Repertoires https://ClinicalTrials.gov/show/NCT01214876 Completed Radboud University 2011-03-31
NCT01196520 Epidemiology of Burkitt Lymphoma in East Africa Children or Minors (EMBLEM) https://ClinicalTrials.gov/show/NCT01196520 Completed National Institutes of Health Clinical Center (CC) 2015-12-31
NCT01190202 Epidemiology Study of Malaria Transmission Intensity in Africa https://ClinicalTrials.gov/show/NCT01190202 Completed GlaxoSmithKline 2013-12-31
NCT01160562 Pilot Study to Estimate the Burden and Distribution of Plasmodium Falciparum Malaria in Kalifabougou, Mali in Preparation for a Prospective Cohort Study of Naturally-Acquired Malaria Immunity https://ClinicalTrials.gov/show/NCT01160562 Completed National Institutes of Health Clinical Center (CC) NA
NCT01115439 Artesunate+Sulfadoxine-Pyrimethamine for the Treatment of Uncomplicated Falciparum Malaria https://ClinicalTrials.gov/show/NCT01115439 Completed University of Oxford 2011-04-30
NCT01120145 Assessment of Sulphadoxine-pyrimethamine for Intermittent Preventive Treatment of Malaria in Pregnancy in Malawi https://ClinicalTrials.gov/show/NCT01120145 Completed Centers for Disease Control and Prevention 2011-01-31
NCT01002066 Effectiveness Of Rapid Diagnostic Tests in the New Context of Low Malaria Endemicity in Zanzibar https://ClinicalTrials.gov/show/NCT01002066 Completed Karolinska University Hospital 2010-10-31
NCT00914225 Effect of Bednets and a Water Purification Device on HIV Disease Progression Among ART naïve Patients in Kenya https://ClinicalTrials.gov/show/NCT00914225 Completed University of Washington 2011-12-31
NCT00913146 Can Treatment of Malaria be Restricted to Parasitologically Confirmed Malaria? https://ClinicalTrials.gov/show/NCT00913146 Completed Institut de Recherche pour le Developpement 2008-06-30
NCT00878098 Study of DDT and Loss of Clinically-Recognized Pregnancies in South Africa https://ClinicalTrials.gov/show/NCT00878098 Completed National Institutes of Health Clinical Center (CC) NA
NCT00873938 Compliance to Artesunate-Amodiaquine Therapy for Uncomplicated Malaria in Rural Ghana https://ClinicalTrials.gov/show/NCT00873938 Completed Kintampo Health Research Centre, Ghana 2006-07-31
NCT00863408 Estivation of Malaria Vector Mosquitoes in the Sahelian Region of Mali https://ClinicalTrials.gov/show/NCT00863408 Completed National Institutes of Health Clinical Center (CC) NA
NCT00850655 Genetic Association Mapping of Malaria Resistance in Anopheles Gambiae https://ClinicalTrials.gov/show/NCT00850655 Completed University of Minnesota 2015-03-31
NCT00840502 Ultrasound Study in Pregnant Women With Malaria https://ClinicalTrials.gov/show/NCT00840502 Active, not recruiting University of Oxford 2019-09-30
NCT01360112 Preventing the Spread of Malaria in Mali https://ClinicalTrials.gov/show/NCT01360112 Completed National Institutes of Health Clinical Center (CC) NA
NCT01168271 Host and Parasite Factors That Influence Susceptibility to Malaria Infection and Disease During Pregnancy and Early Childhood in Ouelessebougou and Bamako, Mali https://ClinicalTrials.gov/show/NCT01168271 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT03483571 Dynamics of Subclinical Malaria: Preliminary Study https://ClinicalTrials.gov/show/NCT03483571 Recruiting Duke University 2021-03-31
NCT02504918 Markers of T Cell Suppression: Associations With Malaria Infection and Antimalarial Treatment in Malian Children https://ClinicalTrials.gov/show/NCT02504918 Completed National Institutes of Health Clinical Center (CC) 2016-12-31
NCT04445103 The Malaria Heart Disease Study https://ClinicalTrials.gov/show/NCT04445103 Recruiting University Hospital, Gentofte, Copenhagen 2023-04-30
NCT02903758 Frequency and Distribution of Mixed Falciparum-vivax Infections in French Guiana https://ClinicalTrials.gov/show/NCT02903758 Completed Centre Hospitalier de Cayenne 2000-01-31
NCT03689036 Transmission Dynamics of Residual and Re-emerging Malaria in the Amazon: Defining a Roadmap to Malaria Elimination https://ClinicalTrials.gov/show/NCT03689036 Recruiting Oswaldo Cruz Foundation 2023-10-31
NCT00772642 Immune Parameters in the Cord Blood of Newborns Exposed to Malaria in the Womb https://ClinicalTrials.gov/show/NCT00772642 Completed National Institutes of Health Clinical Center (CC) NA
NCT00707200 The Cytoadherence in Pediatric Malaria (CPM) Study https://ClinicalTrials.gov/show/NCT00707200 Completed University Health Network, Toronto 2009-11-30
NCT00669084 Innate and Acquired Resistance to Plasmodium Falciparum Malaria in Mali https://ClinicalTrials.gov/show/NCT00669084 Completed National Institutes of Health Clinical Center (CC) NA
NCT00663546 Malaria Studies in Cambodia https://ClinicalTrials.gov/show/NCT00663546 Completed National Institutes of Health Clinical Center (CC) NA
NCT00612547 ACT for the Home Management in Malagasy Children https://ClinicalTrials.gov/show/NCT00612547 Completed National Malaria Control Programme, Madagascar 2009-02-28
NCT00544024 Mefloquine Bioequivalence Among 3 Commercially Available Tablets. https://ClinicalTrials.gov/show/NCT00544024 Completed Centers for Disease Control and Prevention NA
NCT00527163 Role of Nitric Oxide in Malaria https://ClinicalTrials.gov/show/NCT00527163 Completed National Institutes of Health Clinical Center (CC) NA
NCT00508417 Malaria Incidence in Infants in Bancoumana, Mali https://ClinicalTrials.gov/show/NCT00508417 Completed National Institutes of Health Clinical Center (CC) NA
NCT00489619 Safe Pregnancy by Infectious Disease Control https://ClinicalTrials.gov/show/NCT00489619 Completed NICHD Global Network for Women’s and Children’s Health NA
NCT00471666 Medical Implications of Coinfection With Malaria and Filariasis Parasites https://ClinicalTrials.gov/show/NCT00471666 Completed National Institutes of Health Clinical Center (CC) NA
NCT00466557 Plasmodium Resistance in A. Gambiae https://ClinicalTrials.gov/show/NCT00466557 Completed National Institute of Allergy and Infectious Diseases (NIAID) 2012-04-30
NCT00451269 Evaluation of Rapid Diagnosis Tests in Imported Malaria https://ClinicalTrials.gov/show/NCT00451269 Completed Assistance Publique - Hôpitaux de Paris 2010-01-31
NCT00372684 PALUREA: Severe Imported Malaria in Adults https://ClinicalTrials.gov/show/NCT00372684 Completed Assistance Publique - Hôpitaux de Paris 2010-03-31
NCT00414479 Assessment of Anaemia Attributable to Schistosomiasis in School Children in Kenya: Mechanisms and Effect of Treatment https://ClinicalTrials.gov/show/NCT00414479 Completed DBL -Institute for Health Research and Development 2010-01-31
NCT01062386 Malaria Survey in Mbarara District, Uganda 2010 https://ClinicalTrials.gov/show/NCT01062386 Completed Epicentre 2010-02-28
NCT00356824 Relationship Between HIV and Malaria in Ugandan Children https://ClinicalTrials.gov/show/NCT00356824 Completed National Institute of Allergy and Infectious Diseases (NIAID) 2007-04-30
NCT00393757 Malaria Transmission and Immunity in Highland Kenya https://ClinicalTrials.gov/show/NCT00393757 Completed National Institute of Allergy and Infectious Diseases (NIAID) 2011-01-31
NCT00384267 Congenital and Neonatal Malaria in Mali https://ClinicalTrials.gov/show/NCT00384267 Completed National Institute of Allergy and Infectious Diseases (NIAID) 2009-04-30
NCT00368810 Study of Factors Involved in Resistance to Severe Malaria https://ClinicalTrials.gov/show/NCT00368810 Completed National Institutes of Health Clinical Center (CC) NA
NCT00346346 Analysis of the Immune Response to the Malaria Parasite in Mali, West Africa https://ClinicalTrials.gov/show/NCT00346346 Completed National Institutes of Health Clinical Center (CC) NA
NCT00342043 Examination of Protective Factors Against Severe Malaria https://ClinicalTrials.gov/show/NCT00342043 Completed National Institutes of Health Clinical Center (CC) NA
NCT00341003 Severe Malaria and Anti-malarial Drug Resistance in Cambodia https://ClinicalTrials.gov/show/NCT00341003 Completed National Institutes of Health Clinical Center (CC) NA
NCT00338520 Hyperphenylalaninemia in Cerebral Malaria https://ClinicalTrials.gov/show/NCT00338520 Completed University of Utah 2012-01-31
NCT00314899 Fetal Immunity to Falciparum Malaria https://ClinicalTrials.gov/show/NCT00314899 Completed National Institute of Allergy and Infectious Diseases (NIAID) 2009-11-15
NCT00327964 Rapid Diagnostic Tests (RDTs) for Malaria in Kampala, Uganda https://ClinicalTrials.gov/show/NCT00327964 Completed University of California, San Francisco 2006-05-31
NCT00322816 Malaria Prevalence in Children https://ClinicalTrials.gov/show/NCT00322816 Completed National Institute of Allergy and Infectious Diseases (NIAID) 2008-03-31
NCT00322738 Time to Infection With Malaria Parasites https://ClinicalTrials.gov/show/NCT00322738 Completed National Institute of Allergy and Infectious Diseases (NIAID) 2008-03-31
NCT00277849 Collection of Blood From Persons With Hemoglobin and Erythrocyte Polymorphisms for Laboratory Malaria Research https://ClinicalTrials.gov/show/NCT00277849 Completed National Institutes of Health Clinical Center (CC) NA
NCT00164216 Efficacy and Effectiveness of Combined Therapy for Uncomplicated Malaria Treatment in Peru https://ClinicalTrials.gov/show/NCT00164216 Completed Centers for Disease Control and Prevention 2008-03-31
NCT00153491 Adherence to Lumefantrine-Artemether https://ClinicalTrials.gov/show/NCT00153491 Completed Centers for Disease Control and Prevention NA
NCT00138307 Correlates of Protection in Ghana https://ClinicalTrials.gov/show/NCT00138307 Completed National Institute of Allergy and Infectious Diseases (NIAID) NA
NCT00692627 Evaluation of Volume Status, Haemodynamics and Microcirculatory Flow in Adult Patients With Severe Falciparum Malaria https://ClinicalTrials.gov/show/NCT00692627 Completed University of Oxford 2008-12-31

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT02894294 Evaluation of Seasonal Malaria Chemoprevention in Kita https://ClinicalTrials.gov/show/NCT02894294 Completed University of Bamako 2015-03-31
NCT01936766 Optimal Fluid Management in Adult Severe Malaria https://ClinicalTrials.gov/show/NCT01936766 Completed University of Oxford 2017-12-31
NCT03387631 Efficacy And Safety Of AL For The Treatment Of Uncomplicated Falciparum Malaria In Mainland Tanzania https://ClinicalTrials.gov/show/NCT03387631 Completed National Institute for Medical Research, Tanzania 2016-09-30